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AllerMAbs

AllerMAbs

副标题

品牌名称——

AllerMAbs 特约代理

品牌logo——

AllerMAbs


品牌介绍——


Allergy is a prevalent disease in both developedand developing countries. IgE plays a major role in allergic diseases despiteits low expression in the body. Understanding the relationship between IgEresponses and clinical symptoms as well as advancing the IgE detectiontechniques will significantly improve disease management. However, pure IgE israre and expensive, which may hamper research and assay development. IgE mAbs,allergen-specific human IgE mAbs in particular, are also very difficult to prepareeither by hybridoma or recombinant DNA technologies. These obstacles limit thesupply of IgE mAbs on the market. Thus, new technology to produce largequantity and high quality of human IgE mAbs or their equivalents are urgentlyneeded to improve both basic IgE research as well as clinical applications. Wehave designed a proprietary transgenic mouse in conjunction with hybridomatechnologies by which the preparation of IgE hybridomas is more practical andthe production of allergen-specific chimeric human IgE is very efficient. Thesetransgenic mice can be immunized to induce the B cell proliferation to overcomethe limitation of low numbers of human IgE B cells obtained for making IgEhybridomas. Using allergen-immunized transgenic mice to prepare IgE hybridomasproducing allergen-specific chimeric human IgE is also a leading platform inIgE research and production.

Our research team has been studying human IgEand developing antibody production techniques at the Academia Sinica in Taiwansince 2009. We have designed transgenic animals expressing human IgE genes andutilized these animal models to produce IgE mAbs. Recently, we developed a geneknock-in mouse model capable of producing chimeric human IgE antibodies. Usinghybridoma technologies, we successfully prepared IgE hybridomas producingallergen-specific chimeric human IgE mAbs and purified the mAbs by affinitychromatography. Our analyses showed that the chimeric human IgE antibodiesgenerated from our system exhibited equivalent biochemical and biologicalproperties to human IgE. To systematically generate large scale of variouschimeric human IgE mAbs, we founded AllerMAbs Co., Ltd. and signed an exclusivepatent license contract with Academia Sinica. Currently, we are generatingchimeric human IgE mAbs specifically reactive towards different allergencomponents in large scale.


公司网址:http://www.allermabs.com/


AllerMAbs 正式授权安诺伦生物为其中国代理,AllerMAbs 一直以来都是行业的标杆,一直为广大科研客户提供最为优质的产品和服务,北京安诺伦生物致力于为中国科研客户带来最好的产品和服务,签约AllerMAbs 就是为了给广大科研客户带来更加完善的产品和服务,您的满意将是我们最大的荣幸。产品信息欢迎电询:4009658633,010-56256916,联系企业QQ:3198592576,3212874516


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库存产品列表

AllerMAbs

DP120H4

Monoclonal Anti-Der p 1 Chimeric Human IgE

50 μg

AllerMAbs

DP120H4

Monoclonal Anti-Der p 1 Chimeric Human IgE

100 μg

AllerMAbs

DP120H4

Monoclonal Anti-Der p 1 Chimeric Human IgE

200 μg

AllerMAbs

DP120H4

Monoclonal Anti-Der p 1 Chimeric Human IgE

500 μg

AllerMAbs

DP120H4

Monoclonal Anti-Der p 1 Chimeric Human IgE

1 mg

AllerMAbs

DP238F9

Monoclonal Anti-Der p 2 Chimeric Human IgE

50 μg

AllerMAbs

DP238F9

Monoclonal Anti-Der p 2 Chimeric Human IgE

100 μg

AllerMAbs

DP238F9

Monoclonal Anti-Der p 2 Chimeric Human IgE

200 μg

AllerMAbs

DP238F9

Monoclonal Anti-Der p 2 Chimeric Human IgE

500 μg

AllerMAbs

DP238F9

Monoclonal Anti-Der p 2 Chimeric Human IgE

1 mg

AllerMAbs

BV117G2

Monoclonal Anti-Bet v 1 Chimeric Human IgE

50 μg

AllerMAbs

BV117G2

Monoclonal Anti-Bet v 1 Chimeric Human IgE

100 μg

AllerMAbs

BV117G2

Monoclonal Anti-Bet v 1 Chimeric Human IgE

200 μg

AllerMAbs

BV117G2

Monoclonal Anti-Bet v 1 Chimeric Human IgE

500 μg

AllerMAbs

BV117G2

Monoclonal Anti-Bet v 1 Chimeric Human IgE

1 mg

AllerMAbs

OVA8G9

Monoclonal Anti-Ovalbumin Chimeric Human IgE

50 μg

AllerMAbs

OVA8G9

Monoclonal Anti-Ovalbumin Chimeric Human IgE

100 μg

AllerMAbs

OVA8G9

Monoclonal Anti-Ovalbumin Chimeric Human IgE

200 μg

AllerMAbs

OVA8G9

Monoclonal Anti-Ovalbumin Chimeric Human IgE

500 μg

AllerMAbs

OVA8G9

Monoclonal Anti-Ovalbumin Chimeric Human IgE

1 mg

AllerMAbs

PAP1C6

Monoclonal Anti-Papain Chimeric Human IgE

50 μg

AllerMAbs

PAP1C6

Monoclonal Anti-Papain Chimeric Human IgE

100 μg

AllerMAbs

PAP1C6

Monoclonal Anti-Papain Chimeric Human IgE

200 μg

AllerMAbs

PAP1C6

Monoclonal Anti-Papain Chimeric Human IgE

500 μg

AllerMAbs

PAP1C6

Monoclonal Anti-Papain Chimeric Human IgE

1 mg

AllerMAbs

CAS11A2

Monoclonal Anti-Casein Chimeric Human IgE

50 μg

AllerMAbs

CAS11A2

Monoclonal Anti-Casein Chimeric Human IgE

100 μg

AllerMAbs

CAS11A2

Monoclonal Anti-Casein Chimeric Human IgE

200 μg

AllerMAbs

CAS11A2

Monoclonal Anti-Casein Chimeric Human IgE

500 μg

AllerMAbs

CAS11A2

Monoclonal Anti-Casein Chimeric Human IgE

1 mg

AllerMAbs

NON29C11

Monoclonal Chimeric Human IgE Control

100 μg

AllerMAbs

NON29C11

Monoclonal Chimeric Human IgE Control

500 μg

AllerMAbs

NON29C11

Monoclonal Chimeric Human IgE Control

1 mg

AllerMAbs

NON29C11

Monoclonal Chimeric Human IgE Control

5 mg

AllerMAbs

NON29C11

Monoclonal Chimeric Human IgE Control

10 mg


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